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Appreciative Leadership: Building Sustainable Partnerships for Health explores how newly trained graduates and experienced leaders can leverage an interdisciplinary approach focused on the strength of their teams to transform healthcare in today’s complex environment. The text emphasizes how leaders can employ an actionable plan to successfully lead and positively impact health outcomes. The authors convey their approach using the appreciative model—an innovative approach which explores specific appreciative behaviors and what they look like in a complex health care system. The fundamental goal of appreciative leadership is to promote the positive performances of individuals and build on their strengths. In turn, this enables leadership the ability to focus on the alignment of strengths across diverse teams, rather than focusing on weaknesses. As newer models of relationship-based and partnership-driven approaches to leadership move to the forefront, transformative leadership is imperative to meet the demands of today’s complex network-structured health systems.