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From extreme weather events such as Superstorm Sandy, man-made tragedies like the Madrid train bombings, the threat of bioterrorism, and emerging infections such as the H1N1 pandemic flu, disasters are creating increasingly profound threats to health of populations around the globe. Through a presentation of 16 case studies, the authors examine the broad range of public health scenarios through the lens of emergency preparedness and planning. Designed for students across a wide spectrum of health and safety disciplines, this text uniquely demonstrates the application of public health preparedness competencies established by the Association of Schools of Public Health (ASPH).